01One-Stop Glycoprotein AnalysisIdentification and quantification of O- and N-linked glycopeptides along with an automated analysis dramatically simplified analysis processes and reduced time.
02AI Driven Comprehensive Data ManagementAI predictive modeling enables a data-dependent acquisition (DDA) analysis as well as data-independent acquisition (DIA) analysis, which has been a great challenge due to complex data structures.
03Biological Functional Analysis with Integrated VisualizationGO, KEGG, Pfam, Reactome, Interpro, Phosida and STRING are results of functional analysis of protein and glycoprotein, and SpAC9’s user-centric Graphic User Interface (GUI) presents intuitive and ease-of-use visualization reports of the results.
04Massive Data AnalysisHPC Cloud, GPU, or Cluster infra allows up-to 100 times faster search than a traditional CPU based search.
05Biomarker Discovery SolutionSpAC9 rapidly discover disease-related glycoprotein biomarkers which enable healthcare experts to perform a precise diagnosis.
06Complex Project ManagementSpAC9 enables an efficient management of projects and their datasets for individuals and group collaborations.
One-Stop Glycoprotein Analysis
N-Glycopeptides Identification N-linked glycopeptides, with relatively lower sensitivity and abundance, from mass spec. data can be effectively identified and quantified.
O-Glycopeptides IdentificationO-linked glycopeptides, with atypical structure, from mass spec. data can be
rapidly identified and quantified with high accuracy.
Multiple Fragmentation Methods Leveraging multiple fragmentation methods (CID, HCD, HCD+CID, HCD+ETD) in mass spec. provides reliable quantitative results of glycoproteins.
Modifications of GlycansVarious Post-Translational Modifications (PTMs) of glycopeptides occurred during mass spec. operation can be thoroughly analyzed.
Pinpointing of Glycosylation SiteUsing N- and O-linked glycoproteins as well as various tandem mass spectrum methods (ECD, ETD, EThcD) provide a way to assign a specific glycosylation site.
Labeled/Label-free QuantificationWith a database built using theoretical isotope distribution models of O- and N-linked glycopeptides, an accurate qualitative analysis in comparison with mass spec. results and automatic quantitative analysis using the isotope distribution of the LC-MS chromatogram are performed. Also, a thorough quantitative analysis is provided using the various isobaric tags.
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